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Epicordin Brand names, Epicordin Analogs

Epicordin Brand Names Mixture

  • No information avaliable

Epicordin Chemical_Formula

C6H9NO6

Epicordin RX_link

http://www.rxlist.com/cgi/generic/isomono2.htm

Epicordin fda sheet

http://www.fda.gov/cder/foi/anda/98/75-147_Isosorbide.htm

Epicordin msds (material safety sheet)

Epicordin MSDS

Epicordin Synthesis Reference

Hayward et al., Can.J.Chem., 45; 2191-2192 (1967)

Epicordin Molecular Weight

191.139 g/mol

Epicordin Melting Point

88-91oC

Epicordin H2O Solubility

1.07E+005 mg/L

Epicordin State

Solid

Epicordin LogP

-0.15

Epicordin Dosage Forms

Tablet (immediate release); Tablet (extended release)

Epicordin Indication

For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Epicordin Pharmacology

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.

Epicordin Absorption

100%

Epicordin side effects and Toxicity

Symptoms of overdose include vasodilatation, venous pooling, reduced cardiac output, and hypotension. LD50=mg/kg(orally in rat)

Epicordin Patient Information

Epicordin Organisms Affected

Humans and other mammals