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beta-Lindane Brand names, beta-Lindane Analogs

beta-Lindane Brand Names Mixture

  • No information avaliable

beta-Lindane Chemical_Formula

C24H31ClO7

beta-Lindane RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

beta-Lindane fda sheet

beta-Lindane FDA

beta-Lindane msds (material safety sheet)

beta-Lindane MSDS

beta-Lindane Synthesis Reference

No information avaliable

beta-Lindane Molecular Weight

466.951 g/mol

beta-Lindane Melting Point

220-224 oC

beta-Lindane H2O Solubility

5 mg/mL

beta-Lindane State

Solid

beta-Lindane LogP

4.004

beta-Lindane Dosage Forms

Solution; Spray

beta-Lindane Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

beta-Lindane Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

beta-Lindane Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

beta-Lindane side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

beta-Lindane Patient Information

beta-Lindane Organisms Affected

Humans and other mammals