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Gammasan Brand names, Gammasan Analogs

Gammasan Brand Names Mixture

  • No information avaliable

Gammasan Chemical_Formula

C24H31ClO7

Gammasan RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Gammasan fda sheet

Gammasan FDA

Gammasan msds (material safety sheet)

Gammasan MSDS

Gammasan Synthesis Reference

No information avaliable

Gammasan Molecular Weight

466.951 g/mol

Gammasan Melting Point

220-224 oC

Gammasan H2O Solubility

5 mg/mL

Gammasan State

Solid

Gammasan LogP

4.004

Gammasan Dosage Forms

Solution; Spray

Gammasan Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Gammasan Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Gammasan Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Gammasan side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Gammasan Patient Information

Gammasan Organisms Affected

Humans and other mammals