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Gammexane Brand names, Gammexane Analogs

Gammexane Brand Names Mixture

  • No information avaliable

Gammexane Chemical_Formula

C24H31ClO7

Gammexane RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Gammexane fda sheet

Gammexane FDA

Gammexane msds (material safety sheet)

Gammexane MSDS

Gammexane Synthesis Reference

No information avaliable

Gammexane Molecular Weight

466.951 g/mol

Gammexane Melting Point

220-224 oC

Gammexane H2O Solubility

5 mg/mL

Gammexane State

Solid

Gammexane LogP

4.004

Gammexane Dosage Forms

Solution; Spray

Gammexane Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Gammexane Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Gammexane Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Gammexane side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Gammexane Patient Information

Gammexane Organisms Affected

Humans and other mammals