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Devoran Brand names, Devoran Analogs

Devoran Brand Names Mixture

  • No information avaliable

Devoran Chemical_Formula

C24H31ClO7

Devoran RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Devoran fda sheet

Devoran FDA

Devoran msds (material safety sheet)

Devoran MSDS

Devoran Synthesis Reference

No information avaliable

Devoran Molecular Weight

466.951 g/mol

Devoran Melting Point

220-224 oC

Devoran H2O Solubility

5 mg/mL

Devoran State

Solid

Devoran LogP

4.004

Devoran Dosage Forms

Solution; Spray

Devoran Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Devoran Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Devoran Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Devoran side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Devoran Patient Information

Devoran Organisms Affected

Humans and other mammals