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Hexit Brand names, Hexit Analogs

Hexit Brand Names Mixture

  • No information avaliable

Hexit Chemical_Formula

C24H31ClO7

Hexit RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Hexit fda sheet

Hexit FDA

Hexit msds (material safety sheet)

Hexit MSDS

Hexit Synthesis Reference

No information avaliable

Hexit Molecular Weight

466.951 g/mol

Hexit Melting Point

220-224 oC

Hexit H2O Solubility

5 mg/mL

Hexit State

Solid

Hexit LogP

4.004

Hexit Dosage Forms

Solution; Spray

Hexit Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Hexit Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Hexit Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Hexit side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Hexit Patient Information

Hexit Organisms Affected

Humans and other mammals