Fumite lindane
Brand names,
Fumite lindane
Analogs
Fumite lindane
Brand Names Mixture
Fumite lindane
Chemical_Formula
C24H31ClO7
Fumite lindane
RX_link
http://www.rxlist.com/cgi/generic2/lotemax.htm
Fumite lindane
fda sheet
Fumite lindane
msds (material safety sheet)
Fumite lindane
Synthesis Reference
No information avaliable
Fumite lindane
Molecular Weight
466.951 g/mol
Fumite lindane
Melting Point
220-224 oC
Fumite lindane
H2O Solubility
5 mg/mL
Fumite lindane
State
Solid
Fumite lindane
LogP
4.004
Fumite lindane
Dosage Forms
Solution; Spray
Fumite lindane
Indication
As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.
Fumite lindane
Pharmacology
Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.
Fumite lindane
Absorption
Very limited systemic absorption, but good absorption at the point of delivery.
Fumite lindane
side effects and Toxicity
Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.
Fumite lindane
Patient Information
Fumite lindane
Organisms Affected
Humans and other mammals