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Arbitex Brand names, Arbitex Analogs

Arbitex Brand Names Mixture

  • No information avaliable

Arbitex Chemical_Formula

C24H31ClO7

Arbitex RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Arbitex fda sheet

Arbitex FDA

Arbitex msds (material safety sheet)

Arbitex MSDS

Arbitex Synthesis Reference

No information avaliable

Arbitex Molecular Weight

466.951 g/mol

Arbitex Melting Point

220-224 oC

Arbitex H2O Solubility

5 mg/mL

Arbitex State

Solid

Arbitex LogP

4.004

Arbitex Dosage Forms

Solution; Spray

Arbitex Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Arbitex Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Arbitex Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Arbitex side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Arbitex Patient Information

Arbitex Organisms Affected

Humans and other mammals