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beta-BHC Brand names, beta-BHC Analogs

beta-BHC Brand Names Mixture

  • No information avaliable

beta-BHC Chemical_Formula

C24H31ClO7

beta-BHC RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

beta-BHC fda sheet

beta-BHC FDA

beta-BHC msds (material safety sheet)

beta-BHC MSDS

beta-BHC Synthesis Reference

No information avaliable

beta-BHC Molecular Weight

466.951 g/mol

beta-BHC Melting Point

220-224 oC

beta-BHC H2O Solubility

5 mg/mL

beta-BHC State

Solid

beta-BHC LogP

4.004

beta-BHC Dosage Forms

Solution; Spray

beta-BHC Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

beta-BHC Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

beta-BHC Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

beta-BHC side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

beta-BHC Patient Information

beta-BHC Organisms Affected

Humans and other mammals