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Aparasin Brand names, Aparasin Analogs

Aparasin Brand Names Mixture

  • No information avaliable

Aparasin Chemical_Formula

C24H31ClO7

Aparasin RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Aparasin fda sheet

Aparasin FDA

Aparasin msds (material safety sheet)

Aparasin MSDS

Aparasin Synthesis Reference

No information avaliable

Aparasin Molecular Weight

466.951 g/mol

Aparasin Melting Point

220-224 oC

Aparasin H2O Solubility

5 mg/mL

Aparasin State

Solid

Aparasin LogP

4.004

Aparasin Dosage Forms

Solution; Spray

Aparasin Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Aparasin Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Aparasin Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Aparasin side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Aparasin Patient Information

Aparasin Organisms Affected

Humans and other mammals