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Nexit Brand names, Nexit Analogs

Nexit Brand Names Mixture

  • No information avaliable

Nexit Chemical_Formula

C24H31ClO7

Nexit RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Nexit fda sheet

Nexit FDA

Nexit msds (material safety sheet)

Nexit MSDS

Nexit Synthesis Reference

No information avaliable

Nexit Molecular Weight

466.951 g/mol

Nexit Melting Point

220-224 oC

Nexit H2O Solubility

5 mg/mL

Nexit State

Solid

Nexit LogP

4.004

Nexit Dosage Forms

Solution; Spray

Nexit Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Nexit Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Nexit Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Nexit side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Nexit Patient Information

Nexit Organisms Affected

Humans and other mammals