Gamma-BHC dust
Brand names,
Gamma-BHC dust
Analogs
Gamma-BHC dust
Brand Names Mixture
Gamma-BHC dust
Chemical_Formula
C24H31ClO7
Gamma-BHC dust
RX_link
http://www.rxlist.com/cgi/generic2/lotemax.htm
Gamma-BHC dust
fda sheet
Gamma-BHC dust
msds (material safety sheet)
Gamma-BHC dust
Synthesis Reference
No information avaliable
Gamma-BHC dust
Molecular Weight
466.951 g/mol
Gamma-BHC dust
Melting Point
220-224 oC
Gamma-BHC dust
H2O Solubility
5 mg/mL
Gamma-BHC dust
State
Solid
Gamma-BHC dust
LogP
4.004
Gamma-BHC dust
Dosage Forms
Solution; Spray
Gamma-BHC dust
Indication
As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.
Gamma-BHC dust
Pharmacology
Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.
Gamma-BHC dust
Absorption
Very limited systemic absorption, but good absorption at the point of delivery.
Gamma-BHC dust
side effects and Toxicity
Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.
Gamma-BHC dust
Patient Information
Gamma-BHC dust
Organisms Affected
Humans and other mammals