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Chloresene Brand names, Chloresene Analogs

Chloresene Brand Names Mixture

  • No information avaliable

Chloresene Chemical_Formula

C24H31ClO7

Chloresene RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Chloresene fda sheet

Chloresene FDA

Chloresene msds (material safety sheet)

Chloresene MSDS

Chloresene Synthesis Reference

No information avaliable

Chloresene Molecular Weight

466.951 g/mol

Chloresene Melting Point

220-224 oC

Chloresene H2O Solubility

5 mg/mL

Chloresene State

Solid

Chloresene LogP

4.004

Chloresene Dosage Forms

Solution; Spray

Chloresene Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Chloresene Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Chloresene Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Chloresene side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Chloresene Patient Information

Chloresene Organisms Affected

Humans and other mammals