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Aphtiria Brand names, Aphtiria Analogs

Aphtiria Brand Names Mixture

  • No information avaliable

Aphtiria Chemical_Formula

C24H31ClO7

Aphtiria RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Aphtiria fda sheet

Aphtiria FDA

Aphtiria msds (material safety sheet)

Aphtiria MSDS

Aphtiria Synthesis Reference

No information avaliable

Aphtiria Molecular Weight

466.951 g/mol

Aphtiria Melting Point

220-224 oC

Aphtiria H2O Solubility

5 mg/mL

Aphtiria State

Solid

Aphtiria LogP

4.004

Aphtiria Dosage Forms

Solution; Spray

Aphtiria Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Aphtiria Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Aphtiria Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Aphtiria side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Aphtiria Patient Information

Aphtiria Organisms Affected

Humans and other mammals