Bentox 10
Brand names,
Bentox 10
Analogs
Bentox 10
Brand Names Mixture
Bentox 10
Chemical_Formula
C24H31ClO7
Bentox 10
RX_link
http://www.rxlist.com/cgi/generic2/lotemax.htm
Bentox 10
fda sheet
Bentox 10
msds (material safety sheet)
Bentox 10
Synthesis Reference
No information avaliable
Bentox 10
Molecular Weight
466.951 g/mol
Bentox 10
Melting Point
220-224 oC
Bentox 10
H2O Solubility
5 mg/mL
Bentox 10
State
Solid
Bentox 10
LogP
4.004
Bentox 10
Dosage Forms
Solution; Spray
Bentox 10
Indication
As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.
Bentox 10
Pharmacology
Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.
Bentox 10
Absorption
Very limited systemic absorption, but good absorption at the point of delivery.
Bentox 10
side effects and Toxicity
Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.
Bentox 10
Patient Information
Bentox 10
Organisms Affected
Humans and other mammals