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Bexol Brand names, Bexol Analogs

Bexol Brand Names Mixture

  • No information avaliable

Bexol Chemical_Formula

C24H31ClO7

Bexol RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Bexol fda sheet

Bexol FDA

Bexol msds (material safety sheet)

Bexol MSDS

Bexol Synthesis Reference

No information avaliable

Bexol Molecular Weight

466.951 g/mol

Bexol Melting Point

220-224 oC

Bexol H2O Solubility

5 mg/mL

Bexol State

Solid

Bexol LogP

4.004

Bexol Dosage Forms

Solution; Spray

Bexol Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Bexol Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Bexol Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Bexol side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Bexol Patient Information

Bexol Organisms Affected

Humans and other mammals