Murfume grain store smoke
Brand names,
Murfume grain store smoke
Analogs
Murfume grain store smoke
Brand Names Mixture
Murfume grain store smoke
Chemical_Formula
C24H31ClO7
Murfume grain store smoke
RX_link
http://www.rxlist.com/cgi/generic2/lotemax.htm
Murfume grain store smoke
fda sheet
Murfume grain store smoke
msds (material safety sheet)
Murfume grain store smoke
Synthesis Reference
No information avaliable
Murfume grain store smoke
Molecular Weight
466.951 g/mol
Murfume grain store smoke
Melting Point
220-224 oC
Murfume grain store smoke
H2O Solubility
5 mg/mL
Murfume grain store smoke
State
Solid
Murfume grain store smoke
LogP
4.004
Murfume grain store smoke
Dosage Forms
Solution; Spray
Murfume grain store smoke
Indication
As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.
Murfume grain store smoke
Pharmacology
Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.
Murfume grain store smoke
Absorption
Very limited systemic absorption, but good absorption at the point of delivery.
Murfume grain store smoke
side effects and Toxicity
Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.
Murfume grain store smoke
Patient Information
Murfume grain store smoke
Organisms Affected
Humans and other mammals