Viton
Brand names,
Viton
Analogs
Viton
Brand Names Mixture
Viton
Chemical_Formula
C24H31ClO7
Viton
RX_link
http://www.rxlist.com/cgi/generic2/lotemax.htm
Viton
fda sheet
Viton
msds (material safety sheet)
Viton
Synthesis Reference
No information avaliable
Viton
Molecular Weight
466.951 g/mol
Viton
Melting Point
220-224 oC
Viton
H2O Solubility
5 mg/mL
Viton
State
Solid
Viton
LogP
4.004
Viton
Dosage Forms
Solution; Spray
Viton
Indication
As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.
Viton
Pharmacology
Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.
Viton
Absorption
Very limited systemic absorption, but good absorption at the point of delivery.
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side effects and Toxicity
Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.
Viton
Patient Information
Viton
Organisms Affected
Humans and other mammals