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Celanex Brand names, Celanex Analogs

Celanex Brand Names Mixture

  • No information avaliable

Celanex Chemical_Formula

C24H31ClO7

Celanex RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Celanex fda sheet

Celanex FDA

Celanex msds (material safety sheet)

Celanex MSDS

Celanex Synthesis Reference

No information avaliable

Celanex Molecular Weight

466.951 g/mol

Celanex Melting Point

220-224 oC

Celanex H2O Solubility

5 mg/mL

Celanex State

Solid

Celanex LogP

4.004

Celanex Dosage Forms

Solution; Spray

Celanex Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Celanex Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Celanex Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Celanex side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Celanex Patient Information

Celanex Organisms Affected

Humans and other mammals