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Codechine Brand names, Codechine Analogs

Codechine Brand Names Mixture

  • No information avaliable

Codechine Chemical_Formula

C24H31ClO7

Codechine RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Codechine fda sheet

Codechine FDA

Codechine msds (material safety sheet)

Codechine MSDS

Codechine Synthesis Reference

No information avaliable

Codechine Molecular Weight

466.951 g/mol

Codechine Melting Point

220-224 oC

Codechine H2O Solubility

5 mg/mL

Codechine State

Solid

Codechine LogP

4.004

Codechine Dosage Forms

Solution; Spray

Codechine Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Codechine Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Codechine Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Codechine side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Codechine Patient Information

Codechine Organisms Affected

Humans and other mammals