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Lidenal Brand names, Lidenal Analogs

Lidenal Brand Names Mixture

  • No information avaliable

Lidenal Chemical_Formula

C24H31ClO7

Lidenal RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Lidenal fda sheet

Lidenal FDA

Lidenal msds (material safety sheet)

Lidenal MSDS

Lidenal Synthesis Reference

No information avaliable

Lidenal Molecular Weight

466.951 g/mol

Lidenal Melting Point

220-224 oC

Lidenal H2O Solubility

5 mg/mL

Lidenal State

Solid

Lidenal LogP

4.004

Lidenal Dosage Forms

Solution; Spray

Lidenal Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Lidenal Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Lidenal Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Lidenal side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Lidenal Patient Information

Lidenal Organisms Affected

Humans and other mammals