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Lorexane Brand names, Lorexane Analogs

Lorexane Brand Names Mixture

  • No information avaliable

Lorexane Chemical_Formula

C24H31ClO7

Lorexane RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Lorexane fda sheet

Lorexane FDA

Lorexane msds (material safety sheet)

Lorexane MSDS

Lorexane Synthesis Reference

No information avaliable

Lorexane Molecular Weight

466.951 g/mol

Lorexane Melting Point

220-224 oC

Lorexane H2O Solubility

5 mg/mL

Lorexane State

Solid

Lorexane LogP

4.004

Lorexane Dosage Forms

Solution; Spray

Lorexane Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Lorexane Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Lorexane Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Lorexane side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Lorexane Patient Information

Lorexane Organisms Affected

Humans and other mammals