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Lendine Brand names, Lendine Analogs

Lendine Brand Names Mixture

  • No information avaliable

Lendine Chemical_Formula

C24H31ClO7

Lendine RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Lendine fda sheet

Lendine FDA

Lendine msds (material safety sheet)

Lendine MSDS

Lendine Synthesis Reference

No information avaliable

Lendine Molecular Weight

466.951 g/mol

Lendine Melting Point

220-224 oC

Lendine H2O Solubility

5 mg/mL

Lendine State

Solid

Lendine LogP

4.004

Lendine Dosage Forms

Solution; Spray

Lendine Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Lendine Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Lendine Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Lendine side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Lendine Patient Information

Lendine Organisms Affected

Humans and other mammals