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Scabene Brand names, Scabene Analogs

Scabene Brand Names Mixture

  • No information avaliable

Scabene Chemical_Formula

C24H31ClO7

Scabene RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Scabene fda sheet

Scabene FDA

Scabene msds (material safety sheet)

Scabene MSDS

Scabene Synthesis Reference

No information avaliable

Scabene Molecular Weight

466.951 g/mol

Scabene Melting Point

220-224 oC

Scabene H2O Solubility

5 mg/mL

Scabene State

Solid

Scabene LogP

4.004

Scabene Dosage Forms

Solution; Spray

Scabene Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Scabene Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Scabene Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Scabene side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Scabene Patient Information

Scabene Organisms Affected

Humans and other mammals