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Esoderm Brand names, Esoderm Analogs

Esoderm Brand Names Mixture

  • No information avaliable

Esoderm Chemical_Formula

C24H31ClO7

Esoderm RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Esoderm fda sheet

Esoderm FDA

Esoderm msds (material safety sheet)

Esoderm MSDS

Esoderm Synthesis Reference

No information avaliable

Esoderm Molecular Weight

466.951 g/mol

Esoderm Melting Point

220-224 oC

Esoderm H2O Solubility

5 mg/mL

Esoderm State

Solid

Esoderm LogP

4.004

Esoderm Dosage Forms

Solution; Spray

Esoderm Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Esoderm Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Esoderm Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Esoderm side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Esoderm Patient Information

Esoderm Organisms Affected

Humans and other mammals