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Lentox Brand names, Lentox Analogs

Lentox Brand Names Mixture

  • No information avaliable

Lentox Chemical_Formula

C24H31ClO7

Lentox RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Lentox fda sheet

Lentox FDA

Lentox msds (material safety sheet)

Lentox MSDS

Lentox Synthesis Reference

No information avaliable

Lentox Molecular Weight

466.951 g/mol

Lentox Melting Point

220-224 oC

Lentox H2O Solubility

5 mg/mL

Lentox State

Solid

Lentox LogP

4.004

Lentox Dosage Forms

Solution; Spray

Lentox Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Lentox Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Lentox Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Lentox side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Lentox Patient Information

Lentox Organisms Affected

Humans and other mammals