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Heclotox Brand names, Heclotox Analogs

Heclotox Brand Names Mixture

  • No information avaliable

Heclotox Chemical_Formula

C24H31ClO7

Heclotox RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Heclotox fda sheet

Heclotox FDA

Heclotox msds (material safety sheet)

Heclotox MSDS

Heclotox Synthesis Reference

No information avaliable

Heclotox Molecular Weight

466.951 g/mol

Heclotox Melting Point

220-224 oC

Heclotox H2O Solubility

5 mg/mL

Heclotox State

Solid

Heclotox LogP

4.004

Heclotox Dosage Forms

Solution; Spray

Heclotox Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Heclotox Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Heclotox Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Heclotox side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Heclotox Patient Information

Heclotox Organisms Affected

Humans and other mammals