Gexane en es it fr

Gexane Brand names, Gexane Analogs

Gexane Brand Names Mixture

  • No information avaliable

Gexane Chemical_Formula

C24H31ClO7

Gexane RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Gexane fda sheet

Gexane FDA

Gexane msds (material safety sheet)

Gexane MSDS

Gexane Synthesis Reference

No information avaliable

Gexane Molecular Weight

466.951 g/mol

Gexane Melting Point

220-224 oC

Gexane H2O Solubility

5 mg/mL

Gexane State

Solid

Gexane LogP

4.004

Gexane Dosage Forms

Solution; Spray

Gexane Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Gexane Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Gexane Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Gexane side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Gexane Patient Information

Gexane Organisms Affected

Humans and other mammals