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Indane Brand names, Indane Analogs

Indane Brand Names Mixture

  • No information avaliable

Indane Chemical_Formula

C24H31ClO7

Indane RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Indane fda sheet

Indane FDA

Indane msds (material safety sheet)

Indane MSDS

Indane Synthesis Reference

No information avaliable

Indane Molecular Weight

466.951 g/mol

Indane Melting Point

220-224 oC

Indane H2O Solubility

5 mg/mL

Indane State

Solid

Indane LogP

4.004

Indane Dosage Forms

Solution; Spray

Indane Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Indane Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Indane Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Indane side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Indane Patient Information

Indane Organisms Affected

Humans and other mammals