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Ovadziak Brand names, Ovadziak Analogs

Ovadziak Brand Names Mixture

  • No information avaliable

Ovadziak Chemical_Formula

C24H31ClO7

Ovadziak RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Ovadziak fda sheet

Ovadziak FDA

Ovadziak msds (material safety sheet)

Ovadziak MSDS

Ovadziak Synthesis Reference

No information avaliable

Ovadziak Molecular Weight

466.951 g/mol

Ovadziak Melting Point

220-224 oC

Ovadziak H2O Solubility

5 mg/mL

Ovadziak State

Solid

Ovadziak LogP

4.004

Ovadziak Dosage Forms

Solution; Spray

Ovadziak Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Ovadziak Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Ovadziak Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Ovadziak side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Ovadziak Patient Information

Ovadziak Organisms Affected

Humans and other mammals