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Hortex Brand names, Hortex Analogs

Hortex Brand Names Mixture

  • No information avaliable

Hortex Chemical_Formula

C24H31ClO7

Hortex RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Hortex fda sheet

Hortex FDA

Hortex msds (material safety sheet)

Hortex MSDS

Hortex Synthesis Reference

No information avaliable

Hortex Molecular Weight

466.951 g/mol

Hortex Melting Point

220-224 oC

Hortex H2O Solubility

5 mg/mL

Hortex State

Solid

Hortex LogP

4.004

Hortex Dosage Forms

Solution; Spray

Hortex Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Hortex Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Hortex Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Hortex side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Hortex Patient Information

Hortex Organisms Affected

Humans and other mammals