Scabene lotion
Brand names,
Scabene lotion
Analogs
Scabene lotion
Brand Names Mixture
Scabene lotion
Chemical_Formula
C24H31ClO7
Scabene lotion
RX_link
http://www.rxlist.com/cgi/generic2/lotemax.htm
Scabene lotion
fda sheet
Scabene lotion
msds (material safety sheet)
Scabene lotion
Synthesis Reference
No information avaliable
Scabene lotion
Molecular Weight
466.951 g/mol
Scabene lotion
Melting Point
220-224 oC
Scabene lotion
H2O Solubility
5 mg/mL
Scabene lotion
State
Solid
Scabene lotion
LogP
4.004
Scabene lotion
Dosage Forms
Solution; Spray
Scabene lotion
Indication
As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.
Scabene lotion
Pharmacology
Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.
Scabene lotion
Absorption
Very limited systemic absorption, but good absorption at the point of delivery.
Scabene lotion
side effects and Toxicity
Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.
Scabene lotion
Patient Information
Scabene lotion
Organisms Affected
Humans and other mammals