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Gammalin Brand names, Gammalin Analogs

Gammalin Brand Names Mixture

  • No information avaliable

Gammalin Chemical_Formula

C24H31ClO7

Gammalin RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Gammalin fda sheet

Gammalin FDA

Gammalin msds (material safety sheet)

Gammalin MSDS

Gammalin Synthesis Reference

No information avaliable

Gammalin Molecular Weight

466.951 g/mol

Gammalin Melting Point

220-224 oC

Gammalin H2O Solubility

5 mg/mL

Gammalin State

Solid

Gammalin LogP

4.004

Gammalin Dosage Forms

Solution; Spray

Gammalin Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Gammalin Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Gammalin Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Gammalin side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Gammalin Patient Information

Gammalin Organisms Affected

Humans and other mammals