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Aficide Brand names, Aficide Analogs

Aficide Brand Names Mixture

  • No information avaliable

Aficide Chemical_Formula

C24H31ClO7

Aficide RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Aficide fda sheet

Aficide FDA

Aficide msds (material safety sheet)

Aficide MSDS

Aficide Synthesis Reference

No information avaliable

Aficide Molecular Weight

466.951 g/mol

Aficide Melting Point

220-224 oC

Aficide H2O Solubility

5 mg/mL

Aficide State

Solid

Aficide LogP

4.004

Aficide Dosage Forms

Solution; Spray

Aficide Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Aficide Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Aficide Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Aficide side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Aficide Patient Information

Aficide Organisms Affected

Humans and other mammals