TAP 85

TAP 85 Brand names, TAP 85 Analogs

TAP 85 Brand Names Mixture

No information avaliable

TAP 85 Chemical_Formula

C₂₄H₃₁ClO₇

TAP 85 RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

TAP 85 fda sheet

TAP_85 FDA

TAP 85 msds (material safety sheet)

TAP_85 MSDS

TAP 85 Synthesis Reference

No information avaliable

TAP 85 Molecular Weight

466.951 g/mol

TAP 85 Melting Point

220-224 ^oC

TAP 85 H₂O Solubility

5 mg/mL

TAP 85 State

Solid

TAP 85 LogP

4.004

TAP 85 Dosage Forms

Solution; Spray

TAP 85 Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

TAP 85 Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

TAP 85 Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

TAP 85 side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

TAP 85 Patient Information

TAP 85 Organisms Affected

Humans and other mammals