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Thionex Brand names, Thionex Analogs

Thionex Brand Names Mixture

  • No information avaliable

Thionex Chemical_Formula

C24H31ClO7

Thionex RX_link

http://www.rxlist.com/cgi/generic2/lotemax.htm

Thionex fda sheet

Thionex FDA

Thionex msds (material safety sheet)

Thionex MSDS

Thionex Synthesis Reference

No information avaliable

Thionex Molecular Weight

466.951 g/mol

Thionex Melting Point

220-224 oC

Thionex H2O Solubility

5 mg/mL

Thionex State

Solid

Thionex LogP

4.004

Thionex Dosage Forms

Solution; Spray

Thionex Indication

As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.

Thionex Pharmacology

Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.

Thionex Absorption

Very limited systemic absorption, but good absorption at the point of delivery.

Thionex side effects and Toxicity

Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.

Thionex Patient Information

Thionex Organisms Affected

Humans and other mammals