Benzene hexachloride
Brand names,
Benzene hexachloride
Analogs
Benzene hexachloride
Brand Names Mixture
Benzene hexachloride
Chemical_Formula
C24H31ClO7
Benzene hexachloride
RX_link
http://www.rxlist.com/cgi/generic2/lotemax.htm
Benzene hexachloride
fda sheet
Benzene hexachloride
msds (material safety sheet)
Benzene hexachloride
Synthesis Reference
No information avaliable
Benzene hexachloride
Molecular Weight
466.951 g/mol
Benzene hexachloride
Melting Point
220-224 oC
Benzene hexachloride
H2O Solubility
5 mg/mL
Benzene hexachloride
State
Solid
Benzene hexachloride
LogP
4.004
Benzene hexachloride
Dosage Forms
Solution; Spray
Benzene hexachloride
Indication
As an ophthalmic it is used for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, used for the treatment and management of seasonal allergic rhinitis.
Benzene hexachloride
Pharmacology
Loteprednol etabonate (LE) is a "soft" steroid belonging to a unique class of glucocorticoids. LE possesses a metabolically labile 17 beta-chloromethyl ester function which was designed in order to be hydrolyzed to an inactive carboxylic acid moiety. This inactive metabolite is more hydrophilic and is thus readily eliminated from the body. Loteprednol etabonate has good ocular permeation properties and good skin permeation properties similar to "hard" steroids. It is used as a topical agent for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis and iritis.
Benzene hexachloride
Absorption
Very limited systemic absorption, but good absorption at the point of delivery.
Benzene hexachloride
side effects and Toxicity
Adverse effects include abnormal vision / blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia.
Benzene hexachloride
Patient Information
Benzene hexachloride
Organisms Affected
Humans and other mammals