Wagitran
Brand names,
Wagitran
Analogs
Wagitran
Brand Names Mixture
Wagitran
Chemical_Formula
C6H9N3O3
Wagitran
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Wagitran
fda sheet
Wagitran
msds (material safety sheet)
Wagitran
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Wagitran
Molecular Weight
171.154 g/mol
Wagitran
Melting Point
160 oC
Wagitran
H2O Solubility
<0.1g/100mL
Wagitran
State
Solid
Wagitran
LogP
-0.262
Wagitran
Dosage Forms
Tablet; Intravenous injection
Wagitran
Indication
Treatment of acute acne rosacea
Wagitran
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Wagitran
Absorption
Well absorbed
Wagitran
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Wagitran
Patient Information
Wagitran
Organisms Affected
Bacteria and protozoa