Atrivyl
Brand names,
Atrivyl
Analogs
Atrivyl
Brand Names Mixture
Atrivyl
Chemical_Formula
C6H9N3O3
Atrivyl
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Atrivyl
fda sheet
Atrivyl
msds (material safety sheet)
Atrivyl
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Atrivyl
Molecular Weight
171.154 g/mol
Atrivyl
Melting Point
160 oC
Atrivyl
H2O Solubility
<0.1g/100mL
Atrivyl
State
Solid
Atrivyl
LogP
-0.262
Atrivyl
Dosage Forms
Tablet; Intravenous injection
Atrivyl
Indication
Treatment of acute acne rosacea
Atrivyl
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Atrivyl
Absorption
Well absorbed
Atrivyl
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Atrivyl
Patient Information
Atrivyl
Organisms Affected
Bacteria and protozoa