Meronidal
Brand names,
Meronidal
Analogs
Meronidal
Brand Names Mixture
Meronidal
Chemical_Formula
C6H9N3O3
Meronidal
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Meronidal
fda sheet
Meronidal
msds (material safety sheet)
Meronidal
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Meronidal
Molecular Weight
171.154 g/mol
Meronidal
Melting Point
160 oC
Meronidal
H2O Solubility
<0.1g/100mL
Meronidal
State
Solid
Meronidal
LogP
-0.262
Meronidal
Dosage Forms
Tablet; Intravenous injection
Meronidal
Indication
Treatment of acute acne rosacea
Meronidal
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Meronidal
Absorption
Well absorbed
Meronidal
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Meronidal
Patient Information
Meronidal
Organisms Affected
Bacteria and protozoa