Flagyl
Brand names,
Flagyl
Analogs
Flagyl
Brand Names Mixture
Flagyl
Chemical_Formula
C6H9N3O3
Flagyl
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Flagyl
fda sheet
Flagyl
msds (material safety sheet)
Flagyl
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Flagyl
Molecular Weight
171.154 g/mol
Flagyl
Melting Point
160 oC
Flagyl
H2O Solubility
<0.1g/100mL
Flagyl
State
Solid
Flagyl
LogP
-0.262
Flagyl
Dosage Forms
Tablet; Intravenous injection
Flagyl
Indication
Treatment of acute acne rosacea
Flagyl
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Flagyl
Absorption
Well absorbed
Flagyl
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Flagyl
Patient Information
Flagyl
Organisms Affected
Bacteria and protozoa