Nalox
Brand names,
Nalox
Analogs
Nalox
Brand Names Mixture
Nalox
Chemical_Formula
C19H21NO4
Nalox
RX_link
http://www.rxlist.com/cgi/generic3/naloxone.htm
Nalox
fda sheet
Nalox
msds (material safety sheet)
Nalox
Synthesis Reference
No information avaliable
Nalox
Molecular Weight
327.374 g/mol
Nalox
Melting Point
200 - 205 oC
Nalox
H2O Solubility
Soluble
Nalox
State
Solid
Nalox
LogP
1.464
Nalox
Dosage Forms
Liquid
Nalox
Indication
For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids including natural and synthetic narcotics, propoxyphene, methadone and the narcotic-antagonist analgesics: nalbuphine, pentazocine and butorphanol.
Nalox
Pharmacology
Naloxone is an opiate antagonist and prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. Also, it can reverse the psychotomimetic and dysphoric effects of agonist-antagonists such as pentazocine. Naloxone is an essentially pure narcotic antagonist, i.e., it does not possess the "agonistic" or morphine-like properties characteristic of other narcotic antagonists; naloxone does not produce respiratory depression, psychotomimetic effects or pupillary constriction. In the absence of narcotics or agonistic effects of other narcotic antagonists, it exhibits essentially no pharmacologic activity.
Nalox
Absorption
Well absorbed following intramuscular injection.
Nalox
side effects and Toxicity
No information avaliable
Nalox
Patient Information
No information avaliable
Nalox
Organisms Affected
Humans and other mammals