Trichocide
Brand names,
Trichocide
Analogs
Trichocide
Brand Names Mixture
Trichocide
Chemical_Formula
C6H9N3O3
Trichocide
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Trichocide
fda sheet
Trichocide
msds (material safety sheet)
Trichocide
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Trichocide
Molecular Weight
171.154 g/mol
Trichocide
Melting Point
160 oC
Trichocide
H2O Solubility
<0.1g/100mL
Trichocide
State
Solid
Trichocide
LogP
-0.262
Trichocide
Dosage Forms
Tablet; Intravenous injection
Trichocide
Indication
Treatment of acute acne rosacea
Trichocide
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Trichocide
Absorption
Well absorbed
Trichocide
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Trichocide
Patient Information
Trichocide
Organisms Affected
Bacteria and protozoa