Entizol
Brand names,
Entizol
Analogs
Entizol
Brand Names Mixture
Entizol
Chemical_Formula
C6H9N3O3
Entizol
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Entizol
fda sheet
Entizol
msds (material safety sheet)
Entizol
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Entizol
Molecular Weight
171.154 g/mol
Entizol
Melting Point
160 oC
Entizol
H2O Solubility
<0.1g/100mL
Entizol
State
Solid
Entizol
LogP
-0.262
Entizol
Dosage Forms
Tablet; Intravenous injection
Entizol
Indication
Treatment of acute acne rosacea
Entizol
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Entizol
Absorption
Well absorbed
Entizol
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Entizol
Patient Information
Entizol
Organisms Affected
Bacteria and protozoa