Metronidazole Benzoate
Brand names,
Metronidazole Benzoate
Analogs
Metronidazole Benzoate
Brand Names Mixture
Metronidazole Benzoate
Chemical_Formula
C6H9N3O3
Metronidazole Benzoate
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Metronidazole Benzoate
fda sheet
Metronidazole Benzoate
msds (material safety sheet)
Metronidazole Benzoate
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Metronidazole Benzoate
Molecular Weight
171.154 g/mol
Metronidazole Benzoate
Melting Point
160 oC
Metronidazole Benzoate
H2O Solubility
<0.1g/100mL
Metronidazole Benzoate
State
Solid
Metronidazole Benzoate
LogP
-0.262
Metronidazole Benzoate
Dosage Forms
Tablet; Intravenous injection
Metronidazole Benzoate
Indication
Treatment of acute acne rosacea
Metronidazole Benzoate
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Metronidazole Benzoate
Absorption
Well absorbed
Metronidazole Benzoate
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Metronidazole Benzoate
Patient Information
Metronidazole Benzoate
Organisms Affected
Bacteria and protozoa