Sanatrichom
Brand names,
Sanatrichom
Analogs
Sanatrichom
Brand Names Mixture
Sanatrichom
Chemical_Formula
C6H9N3O3
Sanatrichom
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Sanatrichom
fda sheet
Sanatrichom
msds (material safety sheet)
Sanatrichom
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Sanatrichom
Molecular Weight
171.154 g/mol
Sanatrichom
Melting Point
160 oC
Sanatrichom
H2O Solubility
<0.1g/100mL
Sanatrichom
State
Solid
Sanatrichom
LogP
-0.262
Sanatrichom
Dosage Forms
Tablet; Intravenous injection
Sanatrichom
Indication
Treatment of acute acne rosacea
Sanatrichom
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Sanatrichom
Absorption
Well absorbed
Sanatrichom
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Sanatrichom
Patient Information
Sanatrichom
Organisms Affected
Bacteria and protozoa