Takimetol
Brand names,
Takimetol
Analogs
Takimetol
Brand Names Mixture
Takimetol
Chemical_Formula
C6H9N3O3
Takimetol
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Takimetol
fda sheet
Takimetol
msds (material safety sheet)
Takimetol
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Takimetol
Molecular Weight
171.154 g/mol
Takimetol
Melting Point
160 oC
Takimetol
H2O Solubility
<0.1g/100mL
Takimetol
State
Solid
Takimetol
LogP
-0.262
Takimetol
Dosage Forms
Tablet; Intravenous injection
Takimetol
Indication
Treatment of acute acne rosacea
Takimetol
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Takimetol
Absorption
Well absorbed
Takimetol
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Takimetol
Patient Information
Takimetol
Organisms Affected
Bacteria and protozoa