Anagiardil
Brand names,
Anagiardil
Analogs
Anagiardil
Brand Names Mixture
Anagiardil
Chemical_Formula
C6H9N3O3
Anagiardil
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Anagiardil
fda sheet
Anagiardil
msds (material safety sheet)
Anagiardil
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Anagiardil
Molecular Weight
171.154 g/mol
Anagiardil
Melting Point
160 oC
Anagiardil
H2O Solubility
<0.1g/100mL
Anagiardil
State
Solid
Anagiardil
LogP
-0.262
Anagiardil
Dosage Forms
Tablet; Intravenous injection
Anagiardil
Indication
Treatment of acute acne rosacea
Anagiardil
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Anagiardil
Absorption
Well absorbed
Anagiardil
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Anagiardil
Patient Information
Anagiardil
Organisms Affected
Bacteria and protozoa