Helidac
Brand names,
Helidac
Analogs
Helidac
Brand Names Mixture
Helidac
Chemical_Formula
C6H9N3O3
Helidac
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Helidac
fda sheet
Helidac
msds (material safety sheet)
Helidac
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Helidac
Molecular Weight
171.154 g/mol
Helidac
Melting Point
160 oC
Helidac
H2O Solubility
<0.1g/100mL
Helidac
State
Solid
Helidac
LogP
-0.262
Helidac
Dosage Forms
Tablet; Intravenous injection
Helidac
Indication
Treatment of acute acne rosacea
Helidac
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Helidac
Absorption
Well absorbed
Helidac
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Helidac
Patient Information
Helidac
Organisms Affected
Bacteria and protozoa