Metronidazole Hcl
Brand names,
Metronidazole Hcl
Analogs
Metronidazole Hcl
Brand Names Mixture
Metronidazole Hcl
Chemical_Formula
C6H9N3O3
Metronidazole Hcl
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Metronidazole Hcl
fda sheet
Metronidazole Hcl
msds (material safety sheet)
Metronidazole Hcl
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Metronidazole Hcl
Molecular Weight
171.154 g/mol
Metronidazole Hcl
Melting Point
160 oC
Metronidazole Hcl
H2O Solubility
<0.1g/100mL
Metronidazole Hcl
State
Solid
Metronidazole Hcl
LogP
-0.262
Metronidazole Hcl
Dosage Forms
Tablet; Intravenous injection
Metronidazole Hcl
Indication
Treatment of acute acne rosacea
Metronidazole Hcl
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Metronidazole Hcl
Absorption
Well absorbed
Metronidazole Hcl
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Metronidazole Hcl
Patient Information
Metronidazole Hcl
Organisms Affected
Bacteria and protozoa